SCHEMBL2269088

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2269092	1.00	CYP2C9 (0.58)	CYP2C9CYP2C19ALDH1A1KMT2AKDM4E
	SCHEMBL2276179	0.86	CYP2C9 (0.46)	CYP2C9CYP2C19ALDH1A1KMT2AKDM4E
	SCHEMBL2276172	0.86	CYP2C9 (0.46)	CYP2C9CYP2C19ALDH1A1KMT2AKDM4E
	SCHEMBL27716659	0.83	KMT2A (0.62)	ALDH1A1KMT2AKDM4EMEN1POLB
	SCHEMBL2275487	0.81	ACLY (0.61)	ALDH1A1KMT2AKDM4EMEN1POLB
	SCHEMBL2275485	0.81	ACLY (0.61)	ALDH1A1KMT2AKDM4EMEN1POLB
	SCHEMBL13561005	0.80	KMT2A (0.60)	ALDH1A1KMT2AKDM4EMEN1POLB
	SCHEMBL2275112	0.78	CYP2C9 (0.83)	CYP2C9CYP2C19CYP1A2MCL1
	SCHEMBL2271008	0.78	KMT2A (0.56)	ALDH1A1KMT2AKDM4EMEN1POLB
	SCHEMBL5147679	0.78	KMT2A (0.56)	ALDH1A1KMT2AKDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.