Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965781 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL31634578 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL29918238 | 0.87 | KDM4E (0.53) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL7019995 | 0.87 | KDM4E (0.53) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL6811690 | 0.87 | KDM4E (0.49) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL9706363 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL10919244 | 0.85 | KDM4E (0.47) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL13596372 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL29083698 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL866041 | 0.83 | LCK (0.59) | ALDH1A1KDM4EHPGDLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | US | disclosed |
| EP-4247789-A1 | FUNGICIDAL ARYL AMIDINES | Corteva Agriscience LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116529235-A | Fungicidal aryl amidines | 科迪华农业科技有限责任公司 | 2023-08-01 | — | — | CN | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| WO-2022109362-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109362-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-3972414-A1 | FUNGICIDAL ARYL AMIDINES | Corteva Agriscience LLC (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-113613494-A | Fungicidal arylamidines | 科迪华农业科技有限责任公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
| WO-2020237131-A1 | FUNGICIDAL ARYL AMIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020237131-A1 | FUNGICIDAL ARYL AMIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | ALDH1A1 105/4885KDM4E 648/4885HPGD 3589/4885 |
| US-10925848-B2 | Amide derivative | IDO1, IDO2, TPH1 | ALDH1A1 750/4885KDM4E 2941/4885HPGD 550/4885 |
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | ALDH1A1 105/4885KDM4E 648/4885HPGD 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.