SCHEMBL2269336

SCHEMBL2269336

C=C[Si](c1ccccc1)(c1ccccc1)N(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 3/20 0.31
ALDH1A1 P00352 2/20 0.31
GLA P06280 1/20 0.31
TP53 P04637 1/20 0.30
NPC1 O15118 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102541 0.81
SCHEMBL2276682 0.80 MAPT (0.31) MAPTCRHBPCRHR2NPSR1TSHR
SCHEMBL2276504 0.77 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL2101287 0.76
SCHEMBL2267070 0.74
SCHEMBL2276410 0.74 PGR (0.31)
SCHEMBL2274099 0.72 TSHR (0.33) NPSR1TSHR
SCHEMBL2273117 0.72 MEN1 (0.30)
SCHEMBL9979418 0.72 TP53 (0.36) MAPTTSHRALDH1A1GLATP53
SCHEMBL2102622 0.72 KCNH2 (0.39) MAPTTSHRALDH1A1GLATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed