Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682640 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1TTRLMNAMAPT | |
| SCHEMBL3942259 | 0.94 | TTR (0.57) | ALDH1A1TTRLMNAMAPTTSHR | |
| SCHEMBL2747530 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TDP1TTRLMNAMAPT | |
| SCHEMBL2946181 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1TTRLMNAMAPT | |
| SCHEMBL29753668 | 0.85 | TTR (0.64) | ALDH1A1TTRLMNAMAPTTSHR | |
| SCHEMBL223878 | 0.85 | TTR (0.64) | ALDH1A1TTRLMNAMAPTTSHR | |
| SCHEMBL9064356 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TTRLMNAMAPTTSHR | |
| SCHEMBL29689258 | 0.84 | PARP1 (0.55) | ALDH1A1TDP1TTRLMNAMAPT | |
| SCHEMBL310574 | 0.84 | VCAM1 (0.58) | ALDH1A1TDP1LMNAMAPTTSHR | |
| SCHEMBL223645 | 0.84 | PARP1 (0.55) | ALDH1A1TDP1TTRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696611-B2 | Adamantane derivative compound | AMOREPACIFIC CORPORATION (KR) | 2020-06-30 | — | — | US | claimed |
| EP-0440329-A1 | S-substituted carbonyl substituted betathioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-08-07 | — | — | EP | claimed |
| CN-119504570-A | Benzamide compound, pharmaceutical composition and application | 徐州医科大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-114945636-B | Azo compound or salt thereof, polarizing film, polarizing plate, and display device | 日本化药株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-117247387-A | Aromatic heterocyclic compound and preparation method thereof | 上海翊石医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20230391775-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| EP-3187486-B1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORP (KR) | 2023-10-18 | — | — | EP | disclosed |
| CN-116790000-A | Preparation method of colorless polyimide film with low thermal expansion coefficient | 黄山金石木塑料科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-4238975-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Yabao Pharmaceutical R&D Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| CN-114426542-B | Substituted diarylamine compounds, pharmaceutical compositions, preparation method and use thereof | 苏州亚宝药物研发有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116261924-A | Polarizing element, polarizing plate, and display device provided with same | 日本化药株式会社 | 2023-06-13 | — | — | CN | disclosed |
| US-4215114-A | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be | THE UPJOHN COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4197308-A | Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides | THE UPJOHN COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4192885-A | Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides | THE UPJOHN COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4179501-A | Analgesic N-(2-aminocycloaliphatic)azidobenzamides | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4153717-A | 260/332.2 R | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4152459-A | Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides | THE UPJOHN COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4148914-A | Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696611-B2 | Adamantane derivative compound | ADAM8, BACE1, CYP17A1 | ALDH1A1 194/4885TDP1 1151/4885TTR 2911/4885 |
| US-20230391775-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | LRRK2, COMT, PARK7 | ALDH1A1 1791/4885TDP1 678/4885TTR 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.