Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961068 | 0.88 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL9657508 | 0.87 | L3MBTL1 (0.64) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL30825381 | 0.87 | ALDH1A1 (0.62) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL223878 | 0.87 | TTR (0.64) | ALDH1A1LMNAGAAMAPTMEN1 | |
| SCHEMBL29753668 | 0.87 | TTR (0.64) | ALDH1A1LMNAGAAMAPTMEN1 | |
| SCHEMBL4337680 | 0.87 | ALDH1A1 (0.62) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL22698 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL223645 | 0.85 | PARP1 (0.55) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL310574 | 0.85 | VCAM1 (0.58) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL29689258 | 0.85 | PARP1 (0.55) | ALDH1A1LMNAGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206762-A1 | CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-06-26 | — | — | US | disclosed |
| US-20230391775-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| WO-2023192348-A1 | CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-10-05 | — | — | WO | disclosed |
| US-11773118-B2 | Methods of making high enantioselective secondary alcohols | OBI PHARMA, INC. (TW) | 2023-10-03 | — | — | US | disclosed |
| US-11773118-B2 | Methods of making high enantioselective secondary alcohols | OBI PHARMA, INC. (TW) | 2023-10-03 | — | — | US | disclosed |
| EP-4238975-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Yabao Pharmaceutical R&D Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| CN-114426542-B | Substituted diarylamine compounds, pharmaceutical compositions, preparation method and use thereof | 苏州亚宝药物研发有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-110831940-B | New substituted azaindoline derivatives as NIK inhibitors | 詹森药业有限公司 | 2023-06-20 | — | — | CN | disclosed |
| WO-2022089497-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 苏州亚宝药物研发有限公司 | 2022-05-05 | — | — | WO | disclosed |
| CN-114426542-A | Substituted diarylamine compounds, pharmaceutical compositions, methods of preparation and uses thereof | 苏州亚宝药物研发有限公司 | 2022-05-03 | — | — | CN | disclosed |
| WO-2008011045-A2 | 3-ARYL-6-ARYL-7H-[1,2,4]TRIAZOLO[3,4-b][1,3,4]THIADIAZINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20060276490-A1 | Thiopyrimidine and isothiazolopyrimidine Kinase Inhibitors | MICHAELIDES MICHAEL R | 2006-12-07 | — | — | US | disclosed |
| EP-1487841-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | Abbott Laboratories (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20040014756-A1 | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors | ABBVIE INC. | 2004-01-22 | — | — | US | disclosed |
| US-20030225273-A1 | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors | ABBOTT LABORATORIES | 2003-12-04 | — | — | US | disclosed |
| WO-2003080625-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-10-02 | — | — | WO | disclosed |
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5053509-A | Microbiocides; AIDS | LABORATOIRE ROGER BELLON (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0164865-B1 | N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE | THE UPJOHN COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0164865-A1 | N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use | THE UPJOHN COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014756-A1 | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors | ABL1, ERBB2, LCK | ALDH1A1 1463/4885LMNA 4821/4885GAA 2473/4885 |
| US-20060276490-A1 | Thiopyrimidine and isothiazolopyrimidine Kinase Inhibitors | ABL1, LCK, ERBB2 | ALDH1A1 2048/4885LMNA 4827/4885GAA 2232/4885 |
| US-20030225273-A1 | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors | ABL1, ERBB2, LCK | ALDH1A1 1463/4885LMNA 4821/4885GAA 2473/4885 |
| US-20230391775-A1 | SUBSTITUTED DIARYLAMINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | LRRK2, COMT, PARK7 | ALDH1A1 1791/4885LMNA 971/4885GAA 41/4885 |
| US-20250206762-A1 | CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS | OPRM1, TRPA1, ICMT | ALDH1A1 549/4885LMNA 4575/4885GAA 3371/4885 |
| US-11773118-B2 | Methods of making high enantioselective secondary alcohols | ADH5, OSTC, ADH1A | ALDH1A1 91/4885LMNA 4535/4885GAA 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.