Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702029 | 0.80 | SMN1; SMN2 (0.46) | EPHX1EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL172647 | 0.77 | ADH1B (0.40) | EPHX1EPHX2L3MBTL1DRD2DRD3 | |
| SCHEMBL6980363 | 0.72 | LTA4H (0.50) | EPHX1EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL172561 | 0.72 | LTA4H (0.50) | EPHX1EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL13102170 | 0.72 | LTA4H (0.50) | EPHX1EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL13874921 | 0.72 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1DRD2DRD3 | |
| SCHEMBL16380998 | 0.72 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1DRD2DRD3 | |
| SCHEMBL12995614 | 0.72 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1DRD2DRD3 | |
| SCHEMBL13198822 | 0.71 | PABPC1 (0.41) | EPHX1EPHX2L3MBTL1DRD2DRD3 | |
| SCHEMBL24753539 | 0.69 | DRD2 (0.40) | EPHX1EPHX2L3MBTL1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319955-B1 | 6-AMINO-QUINOLINE-3-CARBONITRILS AS COT MODULATORS | GILEAD SCIENCES INC (US) | 2020-11-25 | — | — | EP | disclosed |