SCHEMBL3850181

SCHEMBL3850181

C=CC[SiH](Cl)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715861 0.78 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL8992328 0.77 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL860549 0.76 CYP2C19 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL216362 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL11316909 0.74 CYP2C19 (0.32) ALDH1A1TSHRCYP2C19
SCHEMBL9256810 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL1493083 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9267683 0.73 CYP1A2 (0.35) ALDH1A1TSHRCYP1A2CYP2C19
SCHEMBL9267676 0.73 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19
SCHEMBL7789586 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO claimed
CN-110835354-B Process for preparing alkyl phenyl fluorosilane 张家港市国泰华荣化工新材料有限公司 2022-10-04 CN claimed
CN-113956727-A Colorant composition and coated article 广东华润涂料有限公司 2022-01-21 CN claimed
EP-3180324-B1 HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE ETH ZUERICH (CH) 2020-11-25 EP claimed
CN-110835354-A Process for preparing alkyl phenyl fluorosilane 张家港市国泰华荣化工新材料有限公司 2020-02-25 CN claimed
EP-2982672-A1 Hypervalent iodine CF2CF2X reagents and their use ETH Zurich (CH) 2016-02-10 EP claimed
EP-0488759-B1 Thexyl (C1-C4)alkyl dialkoxy silanes; methods of preparation; and uses thereof SHINETSU CHEMICAL CO (JP) 1994-08-10 EP claimed
EP-0488759-A1 Thexyl (C1-C4)alkyl dialkoxy silanes; methods of preparation; and uses thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-06-03 EP claimed
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO disclosed
CN-110835354-B Process for preparing alkyl phenyl fluorosilane 张家港市国泰华荣化工新材料有限公司 2022-10-04 CN disclosed
CN-110835354-B Process for preparing alkyl phenyl fluorosilane 张家港市国泰华荣化工新材料有限公司 2022-10-04 CN disclosed
EP-3039080-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DUPONT TORAY SPECIALTY MATERIALS KK (JP) 2022-05-11 EP disclosed
CN-113956727-A Colorant composition and coated article 广东华润涂料有限公司 2022-01-21 CN disclosed
CN-113214651-A Curable silicone composition, cured product thereof, and optical semiconductor device 杜邦东丽特殊材料株式会社 2021-08-06 CN disclosed
US-4417782-A Fiber optic temperature sensing RAYCHEM CORPORATION (US) 1983-11-29 US disclosed
US-4373768-A Thermostatic fiber optic waveguides RAYCHEM CORPORATION (US) 1983-02-15 US disclosed
EP-0037266-A2 Method and apparatus for controlling the temperature of or indicating the presence of a material by means of a waveguide, heat activatable articles incorporating waveguides; and novel waveguides and a method of making such waveguides RAYCHEM CORPORATION (a California corporation) (US) 1981-10-07 EP disclosed
EP-0008997-B1 THERMOPLASTIC POLYSTYRENE-DIORGANOPOLYSILOXANE ELASTOMERS AND PROCESS FOR THE MANUFACTURE THEREOF RHONE-POULENC INDUSTRIES (FR) 1981-06-17 EP disclosed
US-4263401-A Thermoplastic, elastomeric polystyrene/diorganopolysiloxane block copolymers RHONE-POULENC INDUSTRIES (FR) 1981-04-21 US disclosed
EP-0008997-A2 Thermoplastic polystyrene-diorganopolysiloxane elastomers and process for the manufacture thereof RHONE-POULENC INDUSTRIES (FR) 1980-03-19 EP disclosed