Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370730 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL12670387 | 0.95 | ALDH1A1 (0.48) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL12670391 | 0.94 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL12370727 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL12370703 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL12370722 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL17011655 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL17011647 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL1905494 | 0.84 | ALDH1A1 (0.34) | ALDH1A1CYP3A4HPGDHSD17B10TDP1 | |
| SCHEMBL11174842 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4ALOX15ALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765261-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-7939580-B2 | Dental composition containing epoxy functional polymerizable compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-7939580-B2 | Dental composition containing epoxy functional polymerizable compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-7915324-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915324-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | 3M DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | 3M DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051488-A1 | Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components | DDX3X, TAS2R39, TAS1R1 | ALDH1A1 1043/4885CYP3A4 1417/4885ALOX15 160/4885 |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | TAS2R41, TAS2R42, TAS1R1 | ALDH1A1 1450/4885CYP3A4 3144/4885ALOX15 537/4885 |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | TAS1R1, TAS2R41, TAS2R39 | ALDH1A1 1136/4885CYP3A4 3027/4885ALOX15 82/4885 |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | EPX, TAS2R41, TAS1R1 | ALDH1A1 1405/4885CYP3A4 2522/4885ALOX15 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.