SCHEMBL2271190

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2273993	0.88	KDM4E (0.55)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL2272413	0.87	MEN1 (0.63)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL2270296	0.81	TDP1 (0.62)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL18152547	0.78	MCL1 (1.00)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL2271422	0.78	LTC4S (0.74)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL2275929	0.78	KMT2A (0.62)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL14075273	0.78	KDM4E (0.63)	MAPTMEN1KMT2AKDM4ENPSR1
	SCHEMBL6350712	0.77	AKR1C2 (0.63)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL4219750	0.76	MCL1 (0.50)	MCL1BCL2A1MAPTMEN1KMT2A
	SCHEMBL25894123	0.76	MCL1 (0.54)	MCL1BCL2A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.