SCHEMBL2273993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2274042	0.88	KDM4E (0.57)	KDM4EMAPK1HSD17B10HDAC3NCOR1
	SCHEMBL2271190	0.88	MCL1 (0.64)	KDM4EMCL1BCL2A1HDAC3NCOR1
	SCHEMBL14428448	0.84	L3MBTL1 (0.50)	KDM4EMCL1BCL2A1MEN1KMT2A
	SCHEMBL2269880	0.83	KDM4E (0.60)	KDM4EMAPK1HSD17B10MEN1KMT2A
	SCHEMBL18152278	0.80	MCL1 (0.78)	KDM4EMAPK1HSD17B10MCL1BCL2A1
	SCHEMBL3165801	0.79	L3MBTL1 (0.52)	MCL1BCL2A1MEN1KMT2AALDH1A1
	SCHEMBL4216703	0.78	MAPT (0.50)	KDM4EMCL1BCL2A1ALDH1A1MAPT
	SCHEMBL2277733	0.77	KDM4E (0.64)	KDM4EMAPK1HSD17B10HDAC1MEN1
	SCHEMBL2275077	0.77	KDM4E (0.66)	KDM4EMAPK1HSD17B10MEN1KMT2A
	SCHEMBL2276099	0.77	KDM4E (0.66)	KDM4EMAPK1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.