SCHEMBL2271979

SCHEMBL2271979

C=C[Si](Cl)(c1ccccc1)C(C)CC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268083 0.81 ALDH1A1 (0.31)
SCHEMBL1313652 0.75 LMNA (0.35) MEN1KMT2ALMNATRPA1
SCHEMBL2102454 0.75 LMNA (0.35) MEN1KMT2ALMNATRPA1
SCHEMBL1315271 0.75 LMNA (0.35) MEN1KMT2ALMNATRPA1
SCHEMBL2272879 0.74 GRIN1 (0.30) MEN1KMT2A
SCHEMBL1317173 0.73 LMNA (0.34) MEN1KMT2ALMNATRPA1
SCHEMBL2267447 0.72 SIGMAR1 (0.33) MEN1KMT2ATRPA1
SCHEMBL2275369 0.72 ALDH1A1 (0.31) MEN1KMT2A
SCHEMBL2273117 0.71 MEN1 (0.30) MEN1KMT2A
SCHEMBL27848783 0.70 LMNA (0.38) MEN1KMT2ALMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed