SCHEMBL2272879

SCHEMBL2272879

C=C[Si](c1ccccc1)(C(C)CC)N(C)C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 4/20 0.30
GRIN2A Q12879 4/20 0.30
GRIN2D O15399 3/20 0.30
GRIN2C Q14957 3/20 0.30
GRIN2B Q13224 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
AOC3 Q16853 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273117 0.87 MEN1 (0.30) MEN1KMT2A
SCHEMBL2269148 0.84
SCHEMBL2272716 0.78 GRIN1 (0.33) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL2276410 0.76 PGR (0.31)
SCHEMBL2103058 0.74 GRIN1 (0.33) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL2271979 0.74 MEN1 (0.31) MEN1KMT2A
SCHEMBL2101028 0.71 AOC3 (0.32) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL2267447 0.71 SIGMAR1 (0.33) MEN1KMT2A
SCHEMBL2275369 0.71 ALDH1A1 (0.31) MEN1KMT2A
SCHEMBL2103846 0.70 SIGMAR1 (0.34) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed