Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24618121 | 0.92 | ALDH1A1 (0.47) | ALDH1A1KDM4ETHRBMAPTSMN1; SMN2 | |
| SCHEMBL22719902 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KDM4ETHRBMAPTSMN1; SMN2 | |
| SCHEMBL22719904 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KDM4ETHRBMAPTSMN1; SMN2 | |
| SCHEMBL3063339 | 0.78 | — | — | |
| SCHEMBL16196894 | 0.78 | — | — | |
| SCHEMBL3063335 | 0.78 | — | — | |
| SCHEMBL2378467 | 0.76 | LMNA (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL17621317 | 0.76 | LMNA (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11971336 | 0.76 | LMNA (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL22726376 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4ETHRBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220067-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | UNIVERSITY OF GUELPH (CA) | 2022-07-14 | — | — | US | disclosed |
| US-20220220067-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | UNIVERSITY OF GUELPH (CA) | 2022-07-14 | — | — | US | disclosed |
| EP-3976580-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | University of Guelph (CA) | 2022-04-06 | — | — | EP | disclosed |
| WO-2020237378-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | UNIVERSITY OF GUELPH (CA) | 2020-12-03 | — | — | WO | disclosed |
| WO-2020237378-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | UNIVERSITY OF GUELPH (CA) | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220067-A1 | PRECURSOR COMPOUNDS OF ESTER COMPOUNDS | HSD17B14, HSD17B12, SDHA | ALDH1A1 267/4885KDM4E 2664/4885THRB 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.