Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738238 | 0.91 | ALDH1A1 (0.37) | MAOBEGLN1HTR2AHTR2C | |
| SCHEMBL22719960 | 0.91 | PPARG (0.38) | PPARGMAOB | |
| SCHEMBL22719901 | 0.91 | EGLN1 (0.35) | PPARGMAOBEGLN1 | |
| SCHEMBL22719921 | 0.90 | NPY5R (0.39) | PPARGMAOBEGLN1 | |
| SCHEMBL22738309 | 0.90 | EGLN1 (0.44) | PPARGEGLN1HTR2C | |
| SCHEMBL22719911 | 0.88 | HTR2A (0.37) | PPARGMAOBEGLN1HTR2AHTR2C | |
| SCHEMBL22738280 | 0.84 | ALDH1A1 (0.51) | PPARGMAOBHTR2AHTR2C | |
| SCHEMBL22738232 | 0.81 | ALDH1A1 (0.35) | MAOB | |
| SCHEMBL22738235 | 0.81 | ALDH1A1 (0.37) | MAOB | |
| SCHEMBL22738287 | 0.81 | MTNR1A (0.41) | PPARGEGLN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237374-A1 | PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2020-12-03 | — | — | WO | disclosed |
| WO-2020237374-A1 | PICOLINIC ACID DERIVATIVES AND USE THEREOF FOR TREATING DISEASES ASSOCIATED WITH ELEVATED CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2020-12-03 | — | — | WO | disclosed |