SCHEMBL2272188

SCHEMBL2272188

CCC[Si](CC)(NC)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274777 0.87 TP53 (0.35) KDM4ECYP3A4MAPTTP53TSHR
SCHEMBL2269776 0.84 GAA (0.33) KMT2AKDM4EMAPTTP53
SCHEMBL28461253 0.81 TP53 (0.33) KMT2AKDM4ECYP3A4MAPTTP53
SCHEMBL2270650 0.80 NAAA (0.36) MAPTTSHR
SCHEMBL28425714 0.76 TP53 (0.36) KDM4ECYP3A4MAPTTP53TSHR
SCHEMBL2101644 0.75 NR1H2 (0.32) KMT2AKDM4ECYP3A4MAPTTP53
SCHEMBL2272184 0.75 KMT2A (0.32) KMT2AKDM4ECYP3A4MAPTTP53
SCHEMBL20499846 0.73 ESR1 (0.33) KMT2AKDM4ECYP3A4MAPTTP53
Dimethylamine SCHEMBL8199596 0.72 ESR1 (0.41) KMT2AKDM4ECYP3A4MAPTTP53
SCHEMBL2102178 0.72 MAPT (0.31) KMT2AKDM4ECYP3A4MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed