SCHEMBL2269776

SCHEMBL2269776

CCC[Si](CC)(NCC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
KCNN4 O15554 1/20 0.32
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ALPL P05186 1/20 0.30
ALOX12 P18054 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272188 0.84 KMT2A (0.31) KDM4EMAPTKMT2ATP53
SCHEMBL28461253 0.81 TP53 (0.33) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2270075 0.80 NAAA (0.36) GAAALDH1A1HPGDKDM4EMAPT
SCHEMBL28425714 0.76 TP53 (0.36) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2102969 0.75 GAA (0.35) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2272798 0.75 GAA (0.35) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2274777 0.74 TP53 (0.35) KDM4EKCNN4MAPTTP53
SCHEMBL2103213 0.72 GAA (0.34) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2268318 0.71 SIGMAR1 (0.36) GAAALDH1A1HPGDKDM4EKCNN4
SCHEMBL2099561 0.70 KCNN4 (0.37) GAAALDH1A1HPGDKDM4EKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed