Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978083 | 0.71 | PARP10 (0.46) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL13176930 | 0.68 | PLA2G7 (0.50) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL5546719 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL24312365 | 0.67 | PARP10 (0.40) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL18944161 | 0.66 | PARP10 (0.39) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL14255914 | 0.65 | PARP10 (0.40) | ALDH1A1MAPTHPGDTP53ALOX15 | |
| SCHEMBL277914 | 0.65 | PLA2G7 (0.67) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL21160781 | 0.64 | PARP10 (0.42) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL23484221 | 0.64 | PARP10 (0.40) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL10921066 | 0.63 | NOTUM (0.50) | ALDH1A1MAPTALOX15PARP10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057950-B1 | PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-02 | — | — | EP | disclosed |