Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10122765 | 0.79 | PARP10 (0.39) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL5546719 | 0.69 | ALDH1A1 (0.58) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL19978083 | 0.69 | PARP10 (0.46) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL21160781 | 0.69 | PARP10 (0.42) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL22726443 | 0.66 | ALDH1A1 (0.39) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL24312365 | 0.66 | PARP10 (0.40) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL23484221 | 0.66 | PARP10 (0.40) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL12461 | 0.64 | DRD2 (0.59) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL14255914 | 0.64 | PARP10 (0.40) | PARP10PARP1PARP11ALDH1A1MAPT | |
| SCHEMBL14255904 | 0.64 | ALDH1A1 (0.47) | PARP10PARP1PARP11ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |