Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728221 | 0.77 | TYR (0.51) | TRPV1ESR1ESR2ESRRBESRRA | |
| SCHEMBL4075615 | 0.71 | ESR1 (0.54) | TRPV1ESR1ESR2ESRRBESRRA | |
| SCHEMBL825930 | 0.65 | MTNR1A (0.40) | MTNR1AMTNR1BROCK2HTR1D | |
| SCHEMBL30448603 | 0.64 | MTNR1A (0.71) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL29032188 | 0.64 | MTNR1A (0.71) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL6978373 | 0.63 | TRPV1 (0.35) | TRPV1ESR1ESR2ESRRBESRRA | |
| SCHEMBL19924462 | 0.63 | ROCK2 (0.35) | MTNR1AMTNR1BROCK2 | |
| SCHEMBL827301 | 0.62 | HTR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL12132426 | 0.62 | LOXL2 (0.50) | PDE10A | |
| SCHEMBL9055794 | 0.61 | ALOX5 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049096-A1 | ANTIFUNGAL COMPOUND PROCESS | VIAMET PHARMACEUTICALS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |