SCHEMBL2273085

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27716665	0.89	HDAC1 (0.62)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL2275453	0.86	ACLY (0.76)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL14428213	0.85	HDAC1 (0.51)	MAPTSUCNR1PTGER4HDAC1HDAC2
	SCHEMBL2273074	0.85	HDAC1 (0.52)	ACLYACMSDMAPTPTGER4HDAC1
	SCHEMBL2275720	0.84	SUCNR1 (0.73)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL2270222	0.83	DHODH (0.77)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL27696833	0.83	HDAC1 (0.46)	ACLYMAPTTDP1PTGER4HDAC1
	SCHEMBL27716606	0.83	HDAC1 (0.69)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL2271193	0.83	ACLY (0.64)	ACLYMEN1PKMKMT2AMAPT
	SCHEMBL2276385	0.82	HDAC2 (0.72)	ACLYMEN1PKMKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.