Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 5/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30316924 | 0.77 | CSNK2A1 (0.39) | CSNK2A1AHRNR4A2CYP2A6MAPK1 | |
| SCHEMBL22004970 | 0.77 | HPGD (0.43) | CSNK2A1AHRNR4A2CYP2A6MAPK1 | |
| SCHEMBL31748733 | 0.77 | GPR84 (0.48) | CSNK2A1AHRNR4A2CMA1F7 | |
| SCHEMBL21672428 | 0.73 | AHR (0.35) | CSNK2A1AHRNR4A2CMA1F7 | |
| SCHEMBL17563335 | 0.73 | GRM1 (0.38) | CSNK2A1AHRNR4A2CMA1F7 | |
| SCHEMBL25954385 | 0.73 | SMN1; SMN2 (0.39) | CSNK2A1AHRNR4A2CMA1F7 | |
| SCHEMBL31162362 | 0.73 | IMPDH2 (0.43) | AHRNR4A2CMA1F7LTA4H | |
| SCHEMBL15410811 | 0.73 | IMPDH2 (0.40) | CSNK2A1AHRNR4A2CYP2A6DYRK1A | |
| SCHEMBL1565481 | 0.71 | CSNK2A1 (0.48) | CSNK2A1AHRNR4A2CYP2A6CMA1 | |
| SCHEMBL30317205 | 0.69 | ALDH1A1 (0.33) | CSNK2A1AHRNR4A2CYP2A6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243459-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-12-03 | — | — | WO | disclosed |