SCHEMBL2273264

SCHEMBL2273264

CNC(=O)c1ccc(O)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.66
GFER P55789 2/20 0.66
CA12 O43570 4/20 0.60
CA1 P00915 4/20 0.60
CA2 P00918 4/20 0.60
CA7 P43166 4/20 0.60
CA9 Q16790 4/20 0.60
CA14 Q9ULX7 4/20 0.60
PDK2 Q15119 1/20 0.60
PDK4 Q16654 1/20 0.60
CES2 O00748 1/20 0.59
TSHR P16473 1/20 0.57
HSP90AB1 P08238 1/20 0.55
KDM4E B2RXH2 2/20 0.54
HTT P42858 2/20 0.54
LMNA P02545 1/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
GAA P10253 3/20 0.53
USP2 O75604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779139 0.83 EGFR (0.62) ALDH1A1GFERCA12CA1CA2
SCHEMBL9785879 0.83 EGFR (0.62) ALDH1A1GFERCA12CA1CA2
SCHEMBL20418534 0.82 TAS1R3 (0.55) TSHRLMNANPC1
SCHEMBL17414618 0.81 NPC1 (0.68) ALDH1A1KDM4EHTTLMNAMEN1
SCHEMBL1436513 0.81 ALDH1A1 (0.68) ALDH1A1GFERCA12CA1CA2
SCHEMBL12216548 0.80 GAA (0.62) ALDH1A1GFERTSHRKDM4ELMNA
SCHEMBL1774955 0.80 GAA (0.48) ALDH1A1GFERCA9CA14CES2
SCHEMBL12678697 0.80 GAA (0.58) ALDH1A1GFERCA12CA1CA2
SCHEMBL19194973 0.80 CA12 (0.53) ALDH1A1GFERCA12CA1CA2
SCHEMBL3814303 0.80 P2RX1 (0.53) ALDH1A1CA1CA2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884021-A Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof 启明大学校产学协力团 2018-11-23 CN claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US claimed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP claimed
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-02 US disclosed
US-11208419-B2 Phenylbenzofuran compound, preparation method therefor, composition containing the same and medical application thereof GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS (CN) 2021-12-28 US disclosed
US-20210198270-A1 PHENYLBENZOFURAN COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING THE SAME AND MEDICAL APPLICATION THEREOF GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS (CN) 2021-07-01 US disclosed
US-20210171883-A1 ANTIVIRAL WIPER FUJIFILM CORPORATION (JP) 2021-06-10 US disclosed
CN-112876419-A Allylamine derivatives, process for producing the same and use thereof 四川科伦博泰生物医药股份有限公司 2021-06-01 CN disclosed
US-10744213-B2 Fluorescent compounds for imaging of blood vessels and blood flow, and an in vivo screen for pro- and anti-angiogenic agents COLOSSUS BIOPHARMA CONSULTANTS COMPANY, LIMITED (TW) 2020-08-18 US disclosed
CN-108884021-A Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof 启明大学校产学协力团 2018-11-23 CN disclosed
EP-2182914-B1 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF L'ORÉAL (FR) 2017-11-08 EP disclosed
US-8043385-B2 Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof L'OREAL S.A. (FR) 2011-10-25 US disclosed
US-8002847-B2 Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes L 'OREAL S.A. (FR) 2011-08-23 US disclosed
US-20100275388-A1 COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES L'OREAL S.A. (FR) 2010-11-04 US disclosed
US-20100263138-A1 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF L'OREAL S.A. (FR) 2010-10-21 US disclosed
EP-2182914-A2 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF L'Oreal (FR) 2010-05-12 EP disclosed
WO-2009019383-A2 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF L'OREAL (FR) 2009-02-12 WO disclosed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US disclosed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP disclosed
EP-0353452-A1 Oxidation hairdyeing composition Henkel Kommanditgesellschaft auf Aktien (DE) 1990-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10744213-B2 Fluorescent compounds for imaging of blood vessels and blood flow, and an in vivo screen for pro- and anti-angiogenic agents FLT4, VEGFA, FLT1 ALDH1A1 2022/4885GFER 4401/4885CA12 2961/4885
US-20210171883-A1 ANTIVIRAL WIPER CGAS, PRKX, PDE4C ALDH1A1 1983/4885GFER 3581/4885CA12 2396/4885
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND PHOSPHO1, RER1, RIF1 ALDH1A1 3361/4885GFER 961/4885CA12 955/4885
US-11208419-B2 Phenylbenzofuran compound, preparation method therefor, composition containing the same and medical application thereof WEE1, WEE2, WASF2 ALDH1A1 3452/4885GFER 3136/4885CA12 1150/4885
US-20210198270-A1 PHENYLBENZOFURAN COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING THE SAME AND MEDICAL APPLICATION THEREOF WEE1, WEE2, WASF2 ALDH1A1 3452/4885GFER 3136/4885CA12 1150/4885
US-20100275388-A1 COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES KRT18, KRTCAP2, FASN ALDH1A1 1792/4885GFER 478/4885CA12 776/4885
US-20100263138-A1 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF KRT18, TUBB3, VIM ALDH1A1 1691/4885GFER 795/4885CA12 578/4885
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses KRT18, CDC73, PYCR1 ALDH1A1 1097/4885GFER 518/4885CA12 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.