SCHEMBL22733

SCHEMBL22733

CC(c1ccc(C(=O)O)c(C(=O)O)c1)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.60
TDP1 Q9NUW8 5/20 0.60
MEN1 O00255 3/20 0.60
CYP2C9 P11712 3/20 0.60
KMT2A Q03164 3/20 0.60
CYP2C19 P33261 2/20 0.60
CYP2D6 P10635 1/20 0.60
GRM8 O00222 1/20 0.60
GRM6 O15303 1/20 0.60
SLC6A2 P23975 1/20 0.60
SLC6A4 P31645 1/20 0.60
DRD3 P35462 1/20 0.60
GRM4 Q14833 1/20 0.60
ALDH1A1 P00352 7/20 0.55
SORT1 Q99523 1/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 4/20 0.43
GRM1 Q13255 3/20 0.43
GRM2 Q14416 2/20 0.43
RXRA P19793 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401129 1.00 HSD17B10 (0.60) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL4531262 0.92 HSD17B10 (0.53) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL10483725 0.91 RXRA (0.55) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL1356399 0.87 HSD17B10 (0.60) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL9853831 0.85 HSD17B10 (0.58) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL18586485 0.83 HSD17B10 (0.67) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL20240085 0.83 MEN1 (0.61) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL2833452 0.83 KDM4E (0.62) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL9860148 0.82 KDM4E (0.57) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL23005779 0.82 ALDH1A1 (0.51) HSD17B10TDP1MEN1CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2139 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368608-B Polyimide composite film for flexible metal-clad foil substrate 达迈科技股份有限公司 2024-02-09 CN claimed
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP claimed
WO-2022265394-A1 BUFFER COMPOSITE SHEET COMPRISING POLYMER FOAM AND POLYIMIDE AND METHOD FOR MANUFACTURING SAME 피아이첨단소재 주식회사 2022-12-22 WO claimed
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO claimed
US-20220339920-A1 POLYIMIDE COMPOSITE FILM FOR USE IN FLEXIBLE METAL CLAD SUBSTRATE TAIMIDE TECHNOLOGY INCORPORATION (TW) 2022-10-27 US claimed
CN-113201136-B Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2022-01-07 CN claimed
CN-113201136-A Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2021-08-03 CN claimed
US-20210179800-A1 DISPENSABLE POLYIMIDE AEROGEL PREPOLYMER, METHOD OF MAKING THE SAME, METHOD OF USING THE SAME, AND SUBSTRATE COMPRISING PATTERNED POLYIMIDE AEROGEL RAYTHEON COMPANY 2021-06-17 US claimed
WO-2021118671-A1 DISPENSABLE POLYIMIDE AEROGEL PREPOLYMER, METHOD OF MAKING THE SAME, METHOD OF USING THE SAME, AND SUBSTRATE COMPRISING PATTERNED POLYIMIDE AEROGEL RAYTHEON COMPANY (US) 2021-06-17 WO claimed
CN-106478968-B A kind of preparation method of nanometer of Kapton 陕西科技大学 2019-06-28 CN claimed
EP-0768559-A1 Polyimide alignment film from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-16 EP claimed
EP-0718312-A2 Crosslinked acidic polysaccharides and their uses HERCULES INCORPORATED (US) 1996-06-26 EP claimed
US-5494991-A REACTING TETRACARBOXYLIC DIANHYDRIDE WITH AROMATIC DIAMINE, HAVING AMIDE AND HYDROXYL GROUPS WHICH DEHYDRATE TO FORM BENZOXAZOLE RING WITHIN THE DIAMINE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-02-27 US claimed
US-5478914-A Polyimides and processes for preparaing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-26 US claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed
US-5003078-A Synthesis of phthalonitrile resins containing ether and imide linkages THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-03-26 US claimed
US-4925915-A FLUORINE CONTAINING POLYIMIDES HOECHST CELANESE CORP. (US) 1990-05-15 US claimed
EP-0317944-A2 Polymers prepared from 4,4'-bis-(2-(amino (halo) phenoxyphenyl) hexafluoroisopropyl) diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
US-4499252-A Process for producing polyimide precursor NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-02-12 US claimed
US-4101487-A HEAT CURABLE AROMATIC DIAMINE-DIACID-AIAMIDE COMPOUND GENERAL ELECTRIC COMPANY (US) 1978-07-18 US claimed