SCHEMBL9860148

SCHEMBL9860148

CC(c1ccc(N)c(C(=O)O)c1)c1ccc(N)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.57
KMT2A Q03164 6/20 0.57
GFER P55789 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
TDP1 Q9NUW8 7/20 0.55
MEN1 O00255 5/20 0.55
MCL1 Q07820 2/20 0.55
USP2 O75604 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55
THRB P10828 1/20 0.55
PKM P14618 1/20 0.55
APEX1 P27695 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
GLA P06280 1/20 0.53
KEAP1 Q14145 1/20 0.53
ALDH1A1 P00352 7/20 0.52
CDC25B P30305 1/20 0.52
CASP6 P55212 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16593497 0.93 TDP1 (0.58) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL4272723 0.89 KDM4E (0.57) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL11090811 0.85 KMT2A (0.53) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL27531056 0.85 KEAP1 (0.58) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL23005779 0.85 ALDH1A1 (0.51) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL4282493 0.82 ALDH1A1 (0.56) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL29401129 0.82 HSD17B10 (0.60) KDM4EKMT2ATDP1MEN1POLB
SCHEMBL22733 0.82 HSD17B10 (0.60) KDM4EKMT2ATDP1MEN1POLB
SCHEMBL28274359 0.81 KDM4E (0.53) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL11089399 0.80 PTGS2 (0.49) KDM4EKMT2AGFERRXFP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021028960-A1 COLORED RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
WO-2021029243-A1 COLORED RESIN COMPOSITION, CURED PRODUCT AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
WO-2020085450-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-04-30 WO disclosed
US-20200048556-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ELEMENT JSR CORPORATION (JP) 2020-02-13 US disclosed
WO-2019244939-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME, AND PRODUCTION METHOD FOR SAID LIQUID CRYSTAL DISPLAY ELEMENT, AND DIAMINE COMPOUND 日産化学株式会社 2019-12-26 WO disclosed
US-9260663-B2 Liquid crystal composition, liquid crystal display, and method for producing liquid crystal display JSR CORPORATION (JP) 2016-02-16 US disclosed
US-20150092147-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY, AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY JSR CORPORATION (JP) 2015-04-02 US disclosed
EP-0171015-B1 PROCESS FOR THE PREPARATION OF STABILIZED POLYAMINES, STABILIZED POLYAMINES WITH RETARDED REACTIVITY AND THEIR USE IN THE PREPARATION OF POLYURETHANE BAYER AG (DE) 1991-03-13 EP disclosed
US-4663415-A STORAGE STABILITY BAYER AKTIENGESELLSCHAFT (DE) 1987-05-05 US disclosed
EP-0171015-A2 Process for the preparation of stabilized polyamines, stabilized polyamines with retarded reactivity and their use in the preparation of polyurethane BAYER AG (DE) 1986-02-12 EP disclosed