Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10386791 | 0.97 | DNM1 (0.48) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27823790 | 0.97 | DNM1 (0.43) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| SCHEMBL29531465 | 0.96 | DNM1 (0.47) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6703153 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27490899 | 0.94 | DNM1 (0.41) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27366250 | 0.94 | DNM1 (0.41) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Iodide SCHEMBL553389 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrogen Sulfide SCHEMBL16734975 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Water SCHEMBL553358 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL15738678 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118040090-A | Electrolyte for inhibiting cathode pulverization of zinc metal battery and battery | 南开大学 | 2024-05-14 | — | — | CN | claimed |
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| US-20220064524-A1 | STABILIZED PEROVSKITE QUANTUM DOT MATERIAL | QUANTUM ADVANCED SOLUTIONS LIMITED (GB) | 2022-03-03 | — | — | US | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| US-9783747-B2 | Process for desulfurization of naphtha using ionic liquids | UOP LLC (US) | 2017-10-10 | — | — | US | claimed |
| CN-107200319-A | One kettle way liquid phase peels off the method for being prepared on a large scale high-quality graphene | 西安交通大学 | 2017-09-26 | — | — | CN | claimed |
| US-20160186232-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2016-06-30 | — | — | US | claimed |
| EP-3031914-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING SAME, AGENT FOR IMPROVING SURFACTANT-RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING SAME | Kikkoman Corporation (JP) | 2016-06-15 | — | — | EP | claimed |
| US-9309471-B2 | Decontamination of deoxygenated biomass-derived pyrolysis oil using ionic liquids | UOP LLC (US) | 2016-04-12 | — | — | US | claimed |
| US-9133403-B2 | Hydrocarbon conversion process to remove metals | UOP LLC (US) | 2015-09-15 | — | — | US | claimed |
| US-20080242825-A1 | Process for making hydrolyzable silylated polymers | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-10-02 | — | — | US | claimed |
| WO-2008118460-A1 | PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| US-20050130228-A1 | Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form | H. LUNDBECK A/S (DK) | 2005-06-16 | — | — | US | claimed |
| US-20030138847-A1 | Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form | H. LUNDBECK A/S (DK) | 2003-07-24 | — | — | US | claimed |
| EP-1268050-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. Lundbeck A/S (DK) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068598-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | claimed |
| EP-0451596-B1 | Phosphonylation process | ALBRIGHT & WILSON (GB) | 1995-07-19 | — | — | EP | claimed |
| EP-0451596-A1 | Phosphonylation process | ALBRIGHT & WILSON LIMITED (GB) | 1991-10-16 | — | — | EP | claimed |
| US-4831166-A | REACTING ALKYLENE OXIDE WITH ACYLACETATE USING IONIC HALIDE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | claimed |
| US-3971817-A | DISPROPORTIONATION OF DIMETHYL-TIN DICHLORIDE AND TIN TETRACHLORIDE | CIBA-GEIGY CORPORATION (US) | 1976-07-27 | — | — | US | claimed |