Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531465 | 0.96 | DNM1 (0.47) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27583907 | 0.94 | TSHR (0.43) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Water SCHEMBL27850385 | 0.94 | TSHR (0.43) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Bromide SCHEMBL1003648 | 0.93 | DNM1 (0.50) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Iodide SCHEMBL553389 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL15738678 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrogen Sulfide SCHEMBL16734975 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL227335 | 0.93 | DNM1 (0.45) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Iodide SCHEMBL17431663 | 0.90 | DNM1 (0.43) | DNM1OPRM1TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27823790 | 0.90 | DNM1 (0.43) | DNM1OPRM1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965788-B | A kind of alkalescence polishing liquid and polishing method | 安集微电子（上海）有限公司 | 2017-10-13 | — | — | CN | claimed |
| CN-118221132-A | Hierarchical pore P-ZSM-5 molecular sieve and preparation method and application thereof | 昆明理工大学 | 2024-06-21 | — | — | CN | disclosed |
| US-20220274052-A1 | ACIDIC GAS SEPARATION MEMBRANE, ACIDIC GAS SEPARATION DEVICE, METHOD FOR PRODUCING ACIDIC GAS SEPARATION MEMBRANE, AND ACIDIC GAS SEPARATION METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-09-01 | — | — | US | disclosed |
| EP-4023327-A1 | ACIDIC GAS SEPARATION MEMBRANE, ACIDIC GAS SEPARATION DEVICE, METHOD FOR PRODUCING ACIDIC GAS SEPARATION MEMBRANE, AND ACIDIC GAS SEPARATION METHOD | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2022-07-06 | — | — | EP | disclosed |
| CN-114600887-A | Auxin herbicide mixtures | 孟山都技术公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114340771-A | Acid gas separation membrane, acid gas separation device, method for producing acid gas separation membrane, and acid gas separation method | 住友化学株式会社 | 2022-04-12 | — | — | CN | disclosed |
| US-11085011-B2 | Post CMP cleaning compositions for ceria particles | ENTEGRIS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| CN-112771144-A | POST chemical mechanical polishing (POST CMP) cleaning composition for cerium particles | 恩特格里斯公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2021039309-A1 | ACIDIC GAS SEPARATION MEMBRANE, ACIDIC GAS SEPARATION DEVICE, METHOD FOR PRODUCING ACIDIC GAS SEPARATION MEMBRANE, AND ACIDIC GAS SEPARATION METHOD | 住友化学株式会社 | 2021-03-04 | — | — | WO | disclosed |
| EP-3638028-A1 | AUXIN HERBICIDAL MIXTURES | Monsanto Technology LLC (US) | 2020-04-22 | — | — | EP | disclosed |
| CN-100394559-C | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | SHINETSU CHEMICAL CO (JP) | 2008-06-11 | — | — | CN | disclosed |
| CN-1501454-A | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | ��Խ��ѧ��ҵ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| US-6207039-B1 | CHARGING SOLUTION CONTAINING ONIUM COMPOUND TO ELECTROCHEMICAL CELL COMPRISING AT LEAST TWO COMPARTMENTS, ONE COMPRISING ION EXCHANGE MATERIAL, CATHODE, ANODE, DIVIDER, PASSING CURRENT THROUGH CELL TO PRODUCE ONIUM SALT, RECOVERING SALT | SACHEM, INC. | 2001-03-27 | — | — | US | disclosed |
| WO-1999051529-A1 | PROCESS FOR RECOVERING ONIUM HYDROXIDES OR ONIUM SALTS FROM SOLUTIONS CONTAINING ONIUM COMPOUNDS USING ELECTROCHEMICAL ION EXCHANGE | SACHEM, INC. (US) | 1999-10-14 | — | — | WO | disclosed |
| US-4405766-A | Phosphonium bicarbonate catalysts for promoting reaction of epoxides with carboxylic acids or anhydrides | THE DOW CHEMICAL COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4354015-A | HIGH MOLECULAR WEIGHT LINEAR EPOXY RESINS | THE DOW CHEMICAL COMPANY (US) | 1982-10-12 | — | — | US | disclosed |
| US-4284573-A | Preparation of glycidyl ethers | THE DOW CHEMICAL COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0002734-B1 | PROCESS FOR THE PREPARATION OF PIPERONYLIDENECROTON AMIDES | HAARMANN & REIMER GMBH (DE) | 1980-09-17 | — | — | EP | disclosed |
| US-4209445-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM HYDROXIDE OR CROWN ETHER METAL COMPLEX | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| EP-0002734-A2 | Process for the preparation of piperonylidenecroton amides | HAARMANN & REIMER GMBH (DE) | 1979-07-11 | — | — | EP | disclosed |