Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5088279 | 0.97 | DNM1 (0.50) | DNM1OPRM1TSHRTHRBCA1 | |
| Hydrochloric Acid SCHEMBL11529307 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRTHRBSPHK1 | |
| Hydrochloric Acid SCHEMBL5087633 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRTHRBSPHK1 | |
| Hydrochloric Acid SCHEMBL5088014 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRTHRBSPHK1 | |
| Hydrochloric Acid SCHEMBL6694560 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRTHRBSPHK1 | |
| Hydrochloric Acid SCHEMBL1925745 | 0.94 | DNM1 (0.55) | DNM1OPRM1TSHRTHRBSPHK1 | |
| Hydrochloric Acid SCHEMBL227335 | 0.94 | DNM1 (0.45) | DNM1OPRM1TSHRTHRBBDKRB2 | |
| SCHEMBL30340673 | 0.90 | DNM1 (0.58) | DNM1OPRM1TSHRTHRBSPHK1 | |
| SCHEMBL30341088 | 0.90 | DNM1 (0.58) | DNM1OPRM1TSHRTHRBSPHK1 | |
| SCHEMBL29702655 | 0.90 | DNM1 (0.58) | DNM1OPRM1TSHRTHRBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040181099-A1 | Aromatic ethers and process for producing aromatic ethers | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181099-A1 | Aromatic ethers and process for producing aromatic ethers | XDH, FTO, CYP4F8 | BDKRB2 2924/4885DNM1 2753/4885OPRM1 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.