SCHEMBL22733865

SCHEMBL22733865

c1csc(-c2csc(-c3cccs3)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.48
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
LTA4H P09960 2/20 0.45
CYP2E1 P05181 1/20 0.45
CYP2A6 P11509 1/20 0.45
CYP2B6 P20813 1/20 0.45
ERN1 O75460 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1273540 0.83 HSD17B1 (0.53) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL22734795 0.82 KCNH2 (0.42) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL22734768 0.82 CYP2A6 (0.45) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL7396854 0.78 KCNH2 (0.46) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL28110998 0.78 KCNH2 (0.55) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL18876430 0.78 KCNH2 (0.46) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL7396852 0.78 KCNH2 (0.46) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL4338418 0.78 KCNH2 (0.58) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL27451260 0.77 KDM4E (0.42) KCNH2CYP3A4CYP2C9LTA4HCYP2E1
SCHEMBL3545 0.77 L3MBTL1 (0.57) KCNH2CYP3A4CYP2C9LTA4HCYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388836-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL TERTHIOPHENE COMPOUND OR THIOPHENE OLIGOMER COMPOUND CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
US-12202954-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-21 US disclosed
US-20230114853-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER MOLDED PRODUCT SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-04-13 US disclosed
US-11605813-B2 Silicon-based energy storage devices with functional terthiophene compound or thiophene oligomer compound containing electrolyte additives ENEVATE CORPORATION (US) 2023-03-14 US disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-20200388836-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL TERTHIOPHENE COMPOUND OR THIOPHENE OLIGOMER COMPOUND CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
US-20200388836-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL TERTHIOPHENE COMPOUND OR THIOPHENE OLIGOMER COMPOUND CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives TST, SELENOI, SELE KCNH2 741/4885CYP3A4 3061/4885CYP2C9 3317/4885
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES TST, SELENOI, SELE KCNH2 741/4885CYP3A4 3061/4885CYP2C9 3317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.