Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27987140 | 0.91 | P2RX7 (0.56) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| SCHEMBL5740191 | 0.81 | P2RX7 (0.52) | P2RX7MAPTL3MBTL1MKNK1MKNK2 | |
| SCHEMBL355358 | 0.81 | P2RX7 (0.52) | P2RX7MAPTL3MBTL1MKNK1MKNK2 | |
| SCHEMBL5073329 | 0.79 | P2RX7 (0.55) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| Hydrochloric Acid SCHEMBL1375608 | 0.79 | P2RX7 (0.50) | P2RX7MAPTL3MBTL1MKNK1MKNK2 | |
| SCHEMBL28905992 | 0.79 | P2RX7 (0.65) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| Hydrochloric Acid SCHEMBL27483686 | 0.79 | P2RX7 (0.55) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| SCHEMBL129457 | 0.79 | P2RX7 (0.65) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| SCHEMBL19310811 | 0.79 | P2RX7 (0.55) | P2RX7MAPTL3MBTL1PARP1MKNK1 | |
| SCHEMBL27543664 | 0.78 | MAPT (0.47) | P2RX7MAPTL3MBTL1PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200385406-A1 | SUBSTITUTED HETEROCYCLIC-PYRIDINONES AS HIV-1 NEF-HCK INHIBITORS | SOUTHERN RESEARCH INSTITUTE | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385406-A1 | SUBSTITUTED HETEROCYCLIC-PYRIDINONES AS HIV-1 NEF-HCK INHIBITORS | HCK, PDXK, NADK | P2RX7 2306/4885MAPT 1498/4885L3MBTL1 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.