Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1375608 | 0.98 | P2RX7 (0.50) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL5740191 | 0.83 | P2RX7 (0.52) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL22734836 | 0.81 | P2RX7 (0.55) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL5073329 | 0.81 | P2RX7 (0.55) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL17210751 | 0.78 | P2RX7 (0.52) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL71547 | 0.78 | KDM4E (0.63) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL29651292 | 0.78 | KDM4E (0.63) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL30599010 | 0.78 | P2RX7 (0.51) | P2RX7KDM4ETDP1NPC1RAB9A | |
| SCHEMBL29086505 | 0.78 | P2RX7 (0.51) | P2RX7KDM4ETDP1NPC1RAB9A | |
| Acetic Acid SCHEMBL27987140 | 0.77 | P2RX7 (0.56) | P2RX7KDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707919-A | Deuterated piperazine compound and preparation method and application thereof | 山东大学 | 2025-03-28 | — | — | CN | claimed |
| WO-2006091506-A2 | NEUROPEPTIDE Y4 RECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-08-31 | — | — | WO | claimed |
| CN-119707919-A | Deuterated piperazine compound and preparation method and application thereof | 山东大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-116874418-A | Process for preparing 2- (methylsulfonyl) nicotinaldehyde | 苏州源起材料科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | UNIV JOHNS HOPKINS (US) | 2023-04-06 | — | — | US | disclosed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| EP-1689421-A4 | SELECTIVE NEUROPEPTIDE Y2 RECEPTOR AGONISTS | BAYER HEALTHCARE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| US-20090105122-A1 | Selective neuropeptide y2 receptor agonists | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-04-23 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5710278-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0692482-A2 | 1-pyridyltetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-4980357-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1990-12-25 | — | — | US | disclosed |
| WO-1989001775-A1 | AZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-03-09 | — | — | WO | disclosed |
| EP-0306251-A2 | Azolidinedione derivatives | PFIZER INC. (US) | 1989-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | P2RX7 620/4885KDM4E 2974/4885TDP1 4059/4885 |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | P2RX7 2058/4885KDM4E 1862/4885TDP1 4434/4885 |
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | SLC26A4, SLC26A3, SLC10A2 | P2RX7 387/4885KDM4E 4800/4885TDP1 4403/4885 |
| US-20090105122-A1 | Selective neuropeptide y2 receptor agonists | NPY2R, NPY1R, NPY4R | P2RX7 297/4885KDM4E 2397/4885TDP1 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.