Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 5/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 5/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22735735 | 0.87 | ATR (0.34) | MAP3K7TAB1ATRROCK2ROCK1 | |
| SCHEMBL22736207 | 0.76 | JAK1 (0.37) | ROCK2ROCK1 | |
| SCHEMBL22735925 | 0.76 | PIK3CD (0.34) | — | |
| SCHEMBL29480529 | 0.76 | BTK (0.42) | ROCK2ROCK1 | |
| SCHEMBL22735884 | 0.76 | BTK (0.42) | ROCK2ROCK1 | |
| SCHEMBL22735888 | 0.74 | LRRK2 (0.34) | ROCK2ROCK1 | |
| SCHEMBL22735724 | 0.70 | JAK1 (0.36) | — | |
| SCHEMBL29480698 | 0.70 | ROCK2 (0.42) | ALDH1A1ROCK2ROCK1 | |
| SCHEMBL22736139 | 0.70 | BTK (0.41) | ROCK2ROCK1 | |
| SCHEMBL31158291 | 0.70 | TLR7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |