Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | GCG | P01275 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29567290 | 0.76 | EGLN1 (0.38) | GRM4GCGEGLN1 | |
| SCHEMBL22736209 | 0.74 | GRM4 (0.35) | GRM4 | |
| SCHEMBL29480647 | 0.72 | MELK (0.51) | GCGEGLN1 | |
| SCHEMBL22736230 | 0.72 | GRM4 (0.38) | GRM4GCGEGLN1 | |
| SCHEMBL29480721 | 0.72 | GRM4 (0.38) | GRM4GCGEGLN1 | |
| SCHEMBL29480652 | 0.71 | EGLN1 (0.34) | GRM4EGLN1 | |
| SCHEMBL22735954 | 0.71 | EGLN1 (0.34) | GRM4EGLN1 | |
| SCHEMBL19288094 | 0.65 | NOS2 (0.35) | — | |
| SCHEMBL29480523 | 0.64 | ADORA2A (0.36) | GRM4GCGEGLN1 | |
| SCHEMBL22716878 | 0.63 | GCG (0.33) | GRM4GCGEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |