SCHEMBL22740372

SCHEMBL22740372

Cc1ccc(N(c2ccccc2)c2ccc3cc4c(cc3c2)sc2cc3sc5cc6cc(N(c7ccccc7)c7ccc(C)cc7)ccc6cc5c3cc24)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C19 P33261 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15852685 0.97 L3MBTL1 (0.38) L3MBTL1HTTNPSR1TDP1CYP2A6
SCHEMBL22739455 0.93 ALDH1A1 (0.36) L3MBTL1TDP1CYP2C19KDM4EALDH1A1
SCHEMBL22739802 0.91 ALDH1A1 (0.35) L3MBTL1TDP1CYP2C19KDM4EALDH1A1
SCHEMBL15852686 0.90 ALDH1A1 (0.38) L3MBTL1TDP1CYP2C19KDM4EALDH1A1
SCHEMBL15852690 0.89 TDP1 (0.36) L3MBTL1HTTNPSR1TDP1CYP2A6
SCHEMBL15852693 0.89 HTT (0.33) L3MBTL1HTTNPSR1ALOX5PTGS1
SCHEMBL22739682 0.88 ALDH1A1 (0.37) L3MBTL1TDP1CYP2C19KDM4EALDH1A1
SCHEMBL22741291 0.88
SCHEMBL22260306 0.88 HTT (0.39) L3MBTL1HTTNPSR1TDP1CYP2A6
SCHEMBL22741952 0.87 APP (0.34) L3MBTL1TDP1CYP2C19KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200377513-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377513-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, TMEM109, LEF1 L3MBTL1 2417/4885HTT 3896/4885NPSR1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.