SCHEMBL227404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19901156	0.96	HRH3 (0.62)	HRH3GPR119EPHX2MLNRCYP11B1
	SCHEMBL3290157	0.87	HRH3 (0.64)	HRH3GPR119EPHX2MLNRFPR2
	SCHEMBL3349865	0.83	HRH3 (0.59)	HRH3GPR119EPHX2MLNRFPR2
	SCHEMBL4380069	0.83	GPR119 (0.65)	HRH3GPR119EPHX2MLNR
	SCHEMBL225375	0.83	GPR119 (0.91)	HRH3GPR119
	SCHEMBL14634277	0.82	GPR119 (0.71)	HRH3GPR119EPHX2MLNRFPR2
	SCHEMBL14634278	0.82	GPR119 (0.71)	HRH3GPR119EPHX2MLNRFPR2
	SCHEMBL16220677	0.82	EPHX2 (0.56)	HRH3EPHX2CYP4F2CYP4A11
	SCHEMBL9013886	0.82	CASP6 (0.53)	HRH3CYP4F2CYP4A11
	SCHEMBL13873173	0.82	GPR119 (0.64)	HRH3GPR119EPHX2MLNRFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.