Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957057 | 0.89 | SCN3A (0.50) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL22746268 | 0.85 | SCN1A (0.57) | ANPEPNAAAATMHSP90AA1SCN3A | |
| SCHEMBL22746450 | 0.83 | ANPEP (0.50) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL1934232 | 0.76 | ANPEP (0.46) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL18487507 | 0.74 | ATM (0.48) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL23317664 | 0.74 | ATM (0.42) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL22781595 | 0.74 | PYGL (0.36) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL28739212 | 0.73 | TSHR (0.53) | ATMHSP90AA1SCN3AMAPTALDH1A1 | |
| SCHEMBL23835699 | 0.73 | SCN3A (0.71) | ANPEPATMHSP90AA1SCN3AMAPT | |
| SCHEMBL24398548 | 0.73 | ANPEP (0.46) | ANPEPATMHSP90AA1SCN3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165812-A1 | NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
| US-20200377459-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377459-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | TRPV1, TRPV2, TRPA1 | ANPEP 1482/4885NAAA 371/4885ATM 4664/4885 |
| US-20230165812-A1 | NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE | OPRL1, MRGPRX1, RAMP1 | ANPEP 783/4885NAAA 2316/4885ATM 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.