Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317806 | 0.76 | PARP1 (0.51) | ADORA3RXFP1DAONPSR1ADORA1 | |
| SCHEMBL30273082 | 0.76 | PARP1 (0.51) | ADORA3RXFP1DAONPSR1ADORA1 | |
| SCHEMBL6288469 | 0.76 | PSMB8 (0.36) | ADORA3RXFP1PSMB8ALDH1A1PARP1 | |
| SCHEMBL29792892 | 0.74 | PARP1 (0.56) | ALDH1A1PARP1HPGDCYP1A2 | |
| SCHEMBL527381 | 0.74 | PARP1 (0.56) | ALDH1A1PARP1HPGDCYP1A2 | |
| SCHEMBL7135462 | 0.74 | ALDH1A1 (0.51) | ADORA3CDC25BADORA1ADORA2AALDH1A1 | |
| SCHEMBL2272351 | 0.74 | ADORA3 (0.36) | ADORA3RXFP1PSMB8NPSR1ALDH1A1 | |
| SCHEMBL13130996 | 0.73 | DAO (0.46) | DAOPARP1GABRPGABRDGABRA1 | |
| SCHEMBL29590166 | 0.72 | POLB (0.38) | ADORA3RXFP1DAOPSMB8NPSR1 | |
| SCHEMBL2270643 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038263-B1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2014-03-05 | — | — | EP | claimed |
| EP-2038263-A1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM Opto Semiconductors GmbH (DE) | 2009-03-25 | — | — | EP | claimed |
| WO-2008006738-A1 | NOVEL AROMATIC AZA HETEROCYCLES, METHOD OF PRODUCTION AND USE OF THE MATERIAL IN ORGANIC ELECTRONICS | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-01-17 | — | — | WO | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20030187188-A1 | Synthesis of peptoid substituted azole compounds | EASTMAN KODAK COMPANY | 2003-10-02 | — | — | US | claimed |
| EP-1319975-A1 | Synthesis of peptoid substituted azole compounds | EASTMAN KODAK COMPANY (US) | 2003-06-18 | — | — | EP | claimed |
| EP-0485423-A1 | PYRAZOLO(1,5-a)BENZIMIDAZOLE COUPLERS. | KODAK LTD (GB) | 1992-05-20 | — | — | EP | claimed |
| WO-1992000299-A1 | PHENOL SUBSTITUTED PYRAZOLO[1,5-a]BENZIMIDAZOLE COUPLERS | EASTMAN KODAK COMPANY (US) | 1992-01-09 | — | — | WO | claimed |
| WO-1991014970-A1 | PYRAZOLO[1,5-a]BENZIMIDAZOLE PHOTOGRAPHIC COLOUR COUPLERS | KODAK LIMITED (GB) | 1991-10-03 | — | — | WO | claimed |
| WO-1991001984-A1 | PYRAZOLO(1,5-a)BENZIMIDAZOLE COUPLERS | EASTMAN KODAK COMPANY (US) | 1991-02-21 | — | — | WO | claimed |
| US-4902604-A | CATIONIC AZULENE DERIVATIVE; PRINTING PLATES, RESISTS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-20 | — | — | US | claimed |
| US-4746600-A | SHARP IMAGES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-05-24 | — | — | US | claimed |
| US-4477563-A | DEVELOPMENT INHIBITION RELEASING COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-16 | — | — | US | claimed |
| US-4395483-A | CHEMICAL FOGGING, METAL AMMINE COMPLEX SALT | FUJI PHOTO FILM CO., LTD. (JP) | 1983-07-26 | — | — | US | claimed |
| US-4146396-A | TWO EQUIVALENT COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1979-03-27 | — | — | US | claimed |
| US-4032346-A | 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187188-A1 | Synthesis of peptoid substituted azole compounds | ERG28, MLNR, DNPEP | ADORA3 1457/4885RXFP1 1017/4885DAO 19/4885 |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | ADORA3 2289/4885RXFP1 4376/4885DAO 9/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | ADORA3 4155/4885RXFP1 4503/4885DAO 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.