Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754848 | 0.80 | KDM4E (0.55) | POLBRAB9AKMT2AALDH1A1ADORA2A | |
| SCHEMBL22755207 | 0.76 | HPGD (0.51) | L3MBTL1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL22755172 | 0.72 | GPR55 (0.56) | RAB9AKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL22755049 | 0.71 | POLB (0.64) | POLBKMT2ASMN1; SMN2 | |
| SCHEMBL22755022 | 0.70 | LIPG (0.40) | POLBRAB9AADORA2A | |
| SCHEMBL22754839 | 0.70 | TP53 (0.39) | POLBRAB9ACYP2C9CYP2C19 | |
| SCHEMBL22755242 | 0.68 | KMT2A (0.57) | POLBRAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL22755258 | 0.68 | LIPG (0.48) | RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL22755180 | 0.67 | MEN1 (0.37) | KMT2A | |
| SCHEMBL24268124 | 0.62 | ALDH1A1 (0.48) | POLBRAB9AKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |