Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754937 | 0.94 | POLB (0.56) | POLBSIGMAR1DRD4 | |
| SCHEMBL22755067 | 0.85 | MDM4 (0.46) | POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22755258 | 0.81 | LIPG (0.48) | — | |
| SCHEMBL22755113 | 0.80 | ADORA2A (0.48) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22754845 | 0.79 | NPC1 (0.50) | POLBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22755022 | 0.78 | LIPG (0.40) | POLB | |
| SCHEMBL22755092 | 0.78 | BACE1 (0.41) | KMT2A | |
| SCHEMBL10778956 | 0.76 | SIGMAR1 (0.71) | POLBSIGMAR1DRD4SLC6A12KMT2A | |
| SCHEMBL22755368 | 0.76 | MTNR1A (0.49) | MAOBLMNA | |
| SCHEMBL22754848 | 0.75 | KDM4E (0.55) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |