Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755107 | 0.89 | RIPK1 (0.47) | EPHX2RBP4HRH1CCR3SPR | |
| SCHEMBL22754904 | 0.86 | CYP46A1 (0.41) | EPHX2CYP2C9CYP2J2HRH1CCR3 | |
| SCHEMBL22755079 | 0.85 | SPR (0.46) | EPHX2HRH1CCR3SPR | |
| SCHEMBL22754898 | 0.85 | NAAA (0.41) | EPHX2CYP2C9RIPK1 | |
| SCHEMBL22729583 | 0.85 | RBP4 (0.41) | EPHX2RBP4CYP2C9CYP2J2CYP2C19 | |
| SCHEMBL22755110 | 0.83 | EPHX2 (0.42) | EPHX2HRH1CCR3SPRHSD11B1 | |
| SCHEMBL22755044 | 0.82 | SCD (0.44) | EPHX2HRH1CCR3 | |
| SCHEMBL22755292 | 0.80 | GRIN2D (0.46) | CYP2C9CYP2C19SPRGRIN2B | |
| SCHEMBL22754905 | 0.80 | HRH1 (0.32) | HRH1CCR3SPR | |
| SCHEMBL22754982 | 0.80 | LIPE (0.43) | EPHX2HRH1CCR3SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |