Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305639 | 0.89 | L3MBTL1 (0.41) | RARBITGB3ITGA2BCTSSCTSK | |
| SCHEMBL22384056 | 0.89 | L3MBTL1 (0.41) | RARBITGB3ITGA2BCTSSCTSK | |
| SCHEMBL22384114 | 0.85 | CTSS (0.44) | CTSSCTSKBCL2 | |
| SCHEMBL22756160 | 0.85 | PSMB5 (0.39) | ITGB3ITGA2BCTSSCTSKBCL2 | |
| SCHEMBL22384055 | 0.84 | L3MBTL1 (0.42) | ITGB3ITGA2BCTSSCTSKBCL2 | |
| SCHEMBL22756131 | 0.82 | CTSS (0.42) | CTSSCTSKBCL2PSMB5PTPN1 | |
| SCHEMBL16294773 | 0.80 | GCGR (0.48) | RARBITGB3ITGA2BCTSSCTSK | |
| SCHEMBL16294771 | 0.80 | GCGR (0.48) | RARBITGB3ITGA2BCTSSCTSK | |
| SCHEMBL17834389 | 0.78 | RARB (0.39) | RARBITGB3ITGA2BSUCNR1 | |
| SCHEMBL16305939 | 0.78 | GCGR (0.48) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |