SCHEMBL2275815

SCHEMBL2275815

N#CC1(C(=O)O)CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CYP2C19 P33261 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.31
AKR1C1 Q04828 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
CACNA2D1 P54289 1/20 0.31
DPP4 P27487 2/20 0.31
FFAR3 O14843 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5125174 1.00 ALDH1A1 (0.44) ALDH1A1CYP2C19SMN1; SMN2AKR1C1USP2
Hydrochloric Acid SCHEMBL10613912 0.98 ALDH1A1 (0.42) ALDH1A1CYP2C19SMN1; SMN2AKR1C1USP2
SCHEMBL2087384 0.97 ALDH1A1 (0.40) ALDH1A1CYP2C19SMN1; SMN2AKR1C1FFAR3
SCHEMBL5551595 0.92
Hydrochloric Acid SCHEMBL11818558 0.90 ALDH1A1 (0.33) ALDH1A1FFAR3
SCHEMBL248308 0.87
SCHEMBL10854389 0.84 ALDH1A1 (0.33) ALDH1A1
Hydrochloric Acid SCHEMBL9422815 0.84
SCHEMBL24663502 0.78 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2DPP4ADORA2AADORA1
SCHEMBL1973159 0.78 ALDH1A1 (0.42) ALDH1A1CYP2C19SMN1; SMN2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003655-A Synthesis method of tranexamic acid 上海巽田科技股份有限公司 2023-11-07 CN claimed
CN-111479802-B Process for producing dicyanocyclohexane and bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2023-07-28 CN claimed
US-11572338-B2 Method for producing dicyanocyclohexane and bis(aminomethyl)cyclohexane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-02-07 US claimed
EP-3733643-B1 METHOD FOR PRODUCING DICYANOCYCLOHEXANE AND BIS(AMINOMETHYL)CYCLOHEXANE MITSUBISHI GAS CHEMICAL CO (JP) 2022-03-23 EP claimed
US-20200392072-A1 METHOD FOR PRODUCING DICYANOCYCLOHEXANE AND BIS(AMINOMETHYL)CYCLOHEXANE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-12-17 US claimed
EP-3733643-A1 METHOD FOR PRODUCING DICYANOCYCLOHEXANE AND BIS(AMINOMETHYL)CYCLOHEXANE Mitsubishi Gas Chemical Company, Inc. (JP) 2020-11-04 EP claimed
CN-111479802-A Process for producing dicyanocyclohexane and bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2020-07-31 CN claimed
US-4028142-A ON IRON, BORON, SILICON ANDOR GROUP 4B TO 6B METALS BY DECOMPOSITION TO PRODUCE DIFFUSION LAYERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US claimed
US-3984451-A Method for preparing hydrazo-bis-acetonitriles PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-10-05 US claimed
US-3972876-A Process for the preparation of symmetrical and unsymmetrical azines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3972874-A Method for preparing symmetrical and unsymmetrical ketazines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
CN-114013386-B Stamping, in particular for permanently closing holes 德莎欧洲股份公司 2024-04-16 CN disclosed
US-11912686-B2 LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2024-02-27 US disclosed
US-20240018118-A1 TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY C 4 Therapeutics, Inc. (US) 2024-01-18 US disclosed
US-20240018118-A1 TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY C 4 Therapeutics, Inc. (US) 2024-01-18 US disclosed
US-4028142-A ON IRON, BORON, SILICON ANDOR GROUP 4B TO 6B METALS BY DECOMPOSITION TO PRODUCE DIFFUSION LAYERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed
US-3984451-A Method for preparing hydrazo-bis-acetonitriles PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-10-05 US disclosed
US-3972876-A Process for the preparation of symmetrical and unsymmetrical azines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US disclosed
US-3972874-A Method for preparing symmetrical and unsymmetrical ketazines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US disclosed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018118-A1 TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY NFATC1, CTSS, MMP12 ALDH1A1 2267/4885CYP2C19 2647/4885SMN1; SMN2 524/4885
US-11572338-B2 Method for producing dicyanocyclohexane and bis(aminomethyl)cyclohexane CPS1, DDC, ACMSD ALDH1A1 3398/4885CYP2C19 3129/4885SMN1; SMN2 4610/4885
US-20200392072-A1 METHOD FOR PRODUCING DICYANOCYCLOHEXANE AND BIS(AMINOMETHYL)CYCLOHEXANE CPS1, DDC, ACMSD ALDH1A1 3398/4885CYP2C19 3129/4885SMN1; SMN2 4610/4885
US-11912686-B2 LPA receptor antagonists and uses thereof LPAR1, LPAR2, LPAR4 ALDH1A1 1726/4885CYP2C19 4398/4885SMN1; SMN2 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.