Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758177 | 0.89 | MALT1 (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22758305 | 0.82 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22758298 | 0.78 | NR4A2 (0.50) | ACHEALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29531928 | 0.77 | PIM2 (0.35) | HPGDSMAPK7 | |
| SCHEMBL6473683 | 0.76 | HPGDS (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29392911 | 0.76 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Hydrochloric Acid SCHEMBL5767708 | 0.76 | ALDH1A1 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20495237 | 0.76 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22758297 | 0.73 | NCF1 (0.44) | ACHEADRA1AALDH1A1 | |
| SCHEMBL9106869 | 0.73 | ACHE (0.54) | MPOACHEALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | CORNELL UNIVERSITY (US) | 2022-02-15 | — | — | US | disclosed |
| US-20200385405-A1 | INHIBITORS OF MALT1 AND USES THEREOF | CORNELL UNIVERSITY (US) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385405-A1 | INHIBITORS OF MALT1 AND USES THEREOF | MALT1, BCL6, BCL3 | GABRA1 1105/4885GABRG2 666/4885GABRB3 1037/4885 |
| US-11248007-B2 | Inhibitors of MALT1 and uses thereof | MALT1, BCL6, BCL3 | GABRA1 1105/4885GABRG2 666/4885GABRB3 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.