SCHEMBL2275992

SCHEMBL2275992

O=S(=O)(O)c1ccc(CC2CO2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 3/20 0.41
PKM P14618 2/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 2/20 0.41
NT5E P21589 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.35
CYP2D6 P10635 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA14 Q9ULX7 2/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189038 0.85 PKM (0.56) LMNAALDH1A1PKMGAATSHR
SCHEMBL4678555 0.82 ALOX5 (0.41) LMNAALDH1A1PKMGAATSHR
SCHEMBL2279315 0.81 ING2 (0.37) LMNAALDH1A1PKMGAATSHR
SCHEMBL5070934 0.80 ALDH1A1 (0.43) LMNAALDH1A1GAASMN1; SMN2MEN1
SCHEMBL131333 0.79 TDP1 (0.38) ALDH1A1TSHRSMN1; SMN2TDP1MEN1
SCHEMBL6295789 0.79 CHRM2 (0.51) LMNAALDH1A1PKMGAATSHR
SCHEMBL3673653 0.75 KMT2A (0.38) LMNAALDH1A1PKMGAAMEN1
SCHEMBL537493 0.75 KMT2A (0.38) LMNAALDH1A1PKMGAAMEN1
SCHEMBL1714161 0.75 AOC2 (0.39) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8763564 0.74 MEN1 (0.46) LMNAALDH1A1GAATSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed
US-7115224-B2 Process for making acid dye stain-resistant fibers PRISMA FIBERS, INC. (US) 2006-10-03 US disclosed
US-6861480-B2 Yarn-forming composition of polyamide and sulfonated acid dye disabler PRISMA FIBERS, INC. (US) 2005-03-01 US disclosed
US-20040154110-A1 Stain-resistant polyamide composition and fibers UNIVERSAL FIBERS, INC. 2004-08-12 US disclosed
US-20040152840-A1 Stain resistant polyamide composition and fibers and method of production thereof PREMIERE FIBERS, INC. 2004-08-05 US disclosed
US-6753385-B2 A REAGENT ASSOCIATES WITH FREE ACID DYE SITES IN A POLYAMIDE; TEXTILE AND CARPET YARNS PRISMA FIBERS, INC. 2004-06-22 US disclosed
US-20040046279-A1 Stain-resistant polyamide composition and fibers and method of production thereof UNIVERSAL FIBERS, INC. 2004-03-11 US disclosed
US-6635346-B2 Polyamide containing acid dye PRISMA FIBERS, INC. 2003-10-21 US disclosed
US-20030138625-A1 Stain-resistant polyamide composition and fibers UNIVERSAL FIBERS, INC. 2003-07-24 US disclosed
US-6537475-B1 Stain resistant fiber forming yarn; melt extruding, disabling free acid dye sites and removing volatiles; spinning and drawing PRISMA FIBERS, INC. 2003-03-25 US disclosed
US-20020155288-A1 Stain-resistant polyamide composition and fibers and method of production thereof UNIVERSAL FIBERS, INC. 2002-10-24 US disclosed
US-6420044-B1 SULFOISOPHTHALIC ACID SALTS; CARRIER IS TERPOLYMER OF AN ALPHA-MONOOLEFIN, AN A,B-UNSATURATED CARBOXYLIC ACID ESTER AND AN INTERNAL ANHYDRIDE OF AN ETHYLENICALLY UNSATURATED CARBOXYLIC ACID; ACID DYES PRISMA FIBERS, INC. 2002-07-16 US disclosed
US-6117550-A CONTAINING AN ALKAL METAL, ALKALINE EARTH METAL OR TRANSITION METAL SALT OF 5-SULFOISOPHTHALIC ACID AND A POLYMERIC BLENDS PRISMA FIBERS, INC. (US) 2000-09-12 US disclosed
WO-1997007962-A1 STAIN-RESISTANT POLYAMIDE COMPOSITION AND FIBERS COOKSON FIBERS, INC., a subsidiary of COOKSON PLC (US) 1997-03-06 WO disclosed