Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 11/20 | 0.41 |
| ▸ | EDNRB | P24530 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760066 | 0.85 | EDNRA (0.43) | EDNRAEDNRBPTGS1PTGS2 | |
| SCHEMBL22760158 | 0.81 | NOTUM (0.41) | EDNRAKMT2A | |
| SCHEMBL22760379 | 0.81 | SMN1; SMN2 (0.35) | KMT2A | |
| SCHEMBL22760364 | 0.81 | FOLH1 (0.37) | EDNRAKMT2A | |
| SCHEMBL22760144 | 0.81 | RPA1 (0.36) | EDNRAEDNRBKMT2A | |
| SCHEMBL22747839 | 0.80 | TSHR (0.43) | EDNRAEDNRBHTR2AHTR2CSLC6A4 | |
| SCHEMBL22747882 | 0.80 | HTT (0.37) | KMT2A | |
| SCHEMBL22760068 | 0.80 | CENPE (0.38) | — | |
| SCHEMBL22760426 | 0.78 | EDNRA (0.39) | EDNRAEDNRBKMT2A | |
| SCHEMBL22748255 | 0.78 | NOTUM (0.41) | EDNRAEDNRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |