Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760364 | 0.91 | FOLH1 (0.37) | NOTUMBCHEKMT2ALMNATSHR | |
| SCHEMBL22748255 | 0.89 | NOTUM (0.41) | NOTUMMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL22760144 | 0.86 | RPA1 (0.36) | NOTUMKMT2ALMNAEDNRARORC | |
| SCHEMBL22747882 | 0.85 | HTT (0.37) | NOTUMMEN1KMT2AMAPK1HPGD | |
| SCHEMBL22760082 | 0.84 | NOTUM (0.38) | NOTUMMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL22760379 | 0.84 | SMN1; SMN2 (0.35) | NOTUMMEN1KMT2ALMNATSHR | |
| SCHEMBL22760085 | 0.83 | EDNRA (0.37) | LMNATSHRALDH1A1EDNRA | |
| SCHEMBL22747829 | 0.83 | FOLH1 (0.35) | NOTUMLMNATSHRALDH1A1EDNRA | |
| SCHEMBL22760140 | 0.83 | NOTUM (0.41) | NOTUMBCHEMEN1KMT2APKM | |
| SCHEMBL22760068 | 0.83 | CENPE (0.38) | NOTUMLMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |