Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 13/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747883 | 0.86 | MAPT (0.50) | ALDH1A1MAPTGAAHPGDTP53 | |
| SCHEMBL22748263 | 0.85 | MAPK8 (0.40) | ALDH1A1MAPTGAAMAPK8HPGD | |
| SCHEMBL22760117 | 0.81 | FOLH1 (0.36) | ALDH1A1MAPTGAAMAPK8TP53 | |
| SCHEMBL22760451 | 0.79 | LMNA (0.34) | ALDH1A1MAPTGAAMAPK8TP53 | |
| SCHEMBL22760095 | 0.77 | MAPT (0.48) | ALDH1A1MAPTGAAHPGDTP53 | |
| SCHEMBL22760414 | 0.73 | EGFR (0.33) | MAPTGAA | |
| SCHEMBL22747868 | 0.71 | FOLH1 (0.35) | ALDH1A1MAPTGAAMAPK8TP53 | |
| SCHEMBL22747829 | 0.71 | FOLH1 (0.35) | ALDH1A1MAPTGAAMAPK8TP53 | |
| SCHEMBL22760173 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAHPGDTP53 | |
| SCHEMBL22760085 | 0.71 | EDNRA (0.37) | ALDH1A1MAPTGAAMAPK8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |