SCHEMBL2276511

SCHEMBL2276511

CN(C)C(=C([SiH3])c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
MAPT P10636 1/20 0.46
HSP90AA1 P07900 1/20 0.40
HIF1A Q16665 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
EGFR P00533 2/20 0.37
KMT2A Q03164 3/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.35
PKM P14618 1/20 0.35
GFER P55789 1/20 0.34
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3281298 0.83 ALDH1A1 (0.56) ALDH1A1MAPTHSP90AA1HIF1AMAOA
SCHEMBL2100174 0.82 ALDH1A1 (0.46) ALDH1A1MAPTHSP90AA1HIF1AMAOA
SCHEMBL2269342 0.77 ALDH1A1 (0.46) ALDH1A1MAPTHIF1AEGFRKMT2A
SCHEMBL6306447 0.76 ALDH1A1 (0.50) ALDH1A1MAPTHSP90AA1HIF1AMAOA
SCHEMBL15900089 0.73 MAPT (0.46) ALDH1A1MAPTHSP90AA1HIF1AMAOA
SCHEMBL5831030 0.70 CES2 (0.44) ALDH1A1MAPTHSP90AA1KMT2ARAB9A
SCHEMBL2276509 0.70 ALDH1A1 (0.48) ALDH1A1MAPTHSP90AA1HIF1AMAOA
SCHEMBL2371664 0.70 ESR1 (0.48) ALDH1A1MAPTHIF1AEGFRKMT2A
SCHEMBL10871237 0.69 ESR1 (0.46) ALDH1A1MAPTRECQLPKMDAO
SCHEMBL8217643 0.68 ALDH1A1 (0.42) ALDH1A1MAPTHSP90AA1HIF1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed