Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533144 | 0.93 | GAA (0.38) | GAAL3MBTL1MDM2DRD2DRD3 | |
| SCHEMBL12533143 | 0.82 | MDM2 (0.33) | GAAL3MBTL1MDM2DRD2DRD3 | |
| SCHEMBL4172165 | 0.78 | GAA (0.38) | GAAL3MBTL1MDM2DRD2DRD3 | |
| SCHEMBL104342 | 0.77 | — | — | |
| SCHEMBL104716 | 0.77 | — | — | |
| SCHEMBL18684792 | 0.77 | GAA (0.43) | GAAL3MBTL1MDM2DRD2DRD3 | |
| SCHEMBL24348617 | 0.76 | — | — | |
| SCHEMBL27385702 | 0.76 | — | — | |
| SCHEMBL19966112 | 0.75 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1 | |
| SCHEMBL22369902 | 0.75 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200384137-A1 | 18F LABELING OF PROTEINS USING SORTASES | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200384137-A1 | 18F LABELING OF PROTEINS USING SORTASES | SORT1, ANPEP, SPG11 | GAA 190/4885L3MBTL1 3554/4885MDM2 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.