SCHEMBL22769435

SCHEMBL22769435

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)NCCN2C(=O)[CH]CC2=O)CCN(CC(=O)O)CC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
KDM4E B2RXH2 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
MEN1 O00255 1/20 0.35
FOLH1 Q04609 4/20 0.35
RECQL P46063 1/20 0.35
CACNA1H O95180 1/20 0.34
CYP2D6 P10635 1/20 0.34
KCNH2 Q12809 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22344789 1.00 ALDH1A1 (0.40) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL1064815 0.83 ALDH1A1 (0.44) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL15362875 0.83 ALDH1A1 (0.44) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL22344785 0.83 ALB (0.49) ALDH1A1SMN1; SMN2KDM4EFOLH1
SCHEMBL7131820 0.76 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2CACNA1H
SCHEMBL15300102 0.76 DRD2 (0.40) ALDH1A1KMT2ASMN1; SMN2TSHRKDM4E
SCHEMBL25039413 0.76 ALDH1A1 (0.40) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL7128542 0.74 ALDH1A1 (0.67) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL15362287 0.74 ITGB3 (0.41) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL10036356 0.74 ITGB3 (0.41) ALDH1A1KMT2ASMN1; SMN2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 US disclosed
CN-108697767-B Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes 安塔罗斯医疗公司 2022-04-15 CN disclosed
EP-3389697-B1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES ANTAROS MEDICAL AB (SE) 2020-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES GIPR, GRPR, GLP1R ALDH1A1 4537/4885KMT2A 3476/4885SMN1; SMN2 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.