SCHEMBL2277993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2276482	0.91	ACLY (0.74)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2272927	0.89	ACLY (0.64)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2272605	0.88	DHODH (0.73)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2272939	0.87	ACLY (0.71)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2269733	0.85	ACLY (0.59)	ACLYSERPINE1SUCNR1GRIK1MEN1
	SCHEMBL2274563	0.85	ACLY (0.81)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2274998	0.84	ACLY (0.80)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2274974	0.84	ACLY (0.67)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL2269365	0.84	MEN1 (0.60)	ACLYSERPINE1SUCNR1DHODHGRIK1
	SCHEMBL30268074	0.83	SERPINE1 (0.60)	ACLYSERPINE1GRIK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.